刚下了avastin官网的用药指南:' `% f' s, `- C# J( H
; B5 B* s6 Y8 i5 ^ Patients should continue treatment until disease progression or unacceptable toxicity.
. Z2 B: W2 @5 W1 Metastatic Colorectal Cancer (mCRC)
9 r6 [6 X0 Z0 B2 B: Q& d+ G% Z; @ The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with ' o5 \1 H5 c0 s3 u' U1 M$ p \' d& E
intravenous 5-FU-based chemotherapy. ; r2 |0 `" l' I3 a% H: X
• Administer 5 mg/kg when used in combination with bolus-IFL. 4 y9 n0 w2 K1 ?/ Q# I' `
• Administer 10 mg/kg when used in combination with FOLFOX4. ) L; m9 V+ @* r& V. H1 P+ Z
2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
! o. y" ]1 w* a The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and
! O+ B0 b4 B; J, y5 @paclitaxel. ( o& c2 b& ?% ?2 X- i
3 Metastatic Breast Cancer (MBC) / _7 }5 Q) _. n/ z' b/ M
The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
, z. A& |. m* |7 w4 Glioblastoma
7 \5 w8 j+ c t$ v4 B The recommended dose is 10 mg/kg every 2 weeks. " k: o3 U; [ c/ h
5 Metastatic Renal Cell Carcinoma (mRCC)6 y2 G; I6 P+ e% M5 b: e% N( i* f
The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa.
4 u/ ?* T5 b% y$ J9 }
1 C* O1 \ A! I: N: S按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。
5 K+ _1 N) A$ u6 A; ^ C( ]+ o. A我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |